{"id":1130,"date":"2024-09-06T08:55:33","date_gmt":"2024-09-06T00:55:33","guid":{"rendered":"https:\/\/antuobang.shchildren.com.cn\/?p=1130"},"modified":"2024-09-25T15:51:29","modified_gmt":"2024-09-25T07:51:29","slug":"tourette%e7%bb%bc%e5%90%88%e5%be%81%e6%9c%80%e6%96%b0%e7%a0%94%e7%a9%b6%e4%ba%ae%e7%82%b9%e5%88%86%e4%ba%ab%ef%bc%88%e4%ba%8c%ef%bc%89","status":"publish","type":"post","link":"https:\/\/antuobang.shchildren.com.cn\/?p=1130","title":{"rendered":"Tourette\u7efc\u5408\u5f81\u6700\u65b0\u7814\u7a76\u4eae\u70b9\u5206\u4eab\uff08\u4e8c\uff09"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"1130\" class=\"elementor elementor-1130\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-6f1ba129 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"6f1ba129\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3218655f\" data-id=\"3218655f\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1454b9d1 elementor-widget__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"1454b9d1\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.14.0 - 18-06-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p><!-- wp:paragraph --><\/p>\n<p>\u4f5c\u8005\uff1a\u8881\u82b3\u4e3b\u6cbb\u533b\u5e08<\/p>\n<p>\u5927\u5bb6\u597d\uff01\u5c0f\u524d\u6cbf\u53c8\u548c\u5927\u5bb6\u89c1\u9762\u4e86\uff0c\u672c\u671f\u7ee7\u7eed\u5206\u4eab2023\u5e7410\u6708\u53d1\u8868\u5728F1000Research\u5e73\u53f0\u7684\u4e00\u7bc7\u7efc\u8ff0\u300aTourette syndrome research highlights from 2022\u300b\u3002<\/p>\n<p><!-- \/wp:paragraph --><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d3b2515 elementor-widget elementor-widget-text-editor\" data-id=\"d3b2515\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u6d41\u884c\u75c5\u5b66<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5f995a6 elementor-widget elementor-widget-text-editor\" data-id=\"5f995a6\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u4e00\u4e9b\u7814\u7a76\u63a2\u8ba8\u4e86 Tourette \u7efc\u5408\u5f81\uff08Tourette syndrome\uff0cTS\uff09 \u548c\u6162\u6027\u62bd\u52a8\u969c\u788d\uff08Chronic tic disorders, CTD\uff09\u7684\u60a3\u75c5\u7387\u548c\u53d1\u75c5\u7387\u3002\u6839\u636e 2016-2017 \u5e74\u5168\u56fd\uff08\u7f8e\u56fd\uff09\u513f\u7ae5\u5065\u5eb7\u8c03\u67e5\u6570\u636e\u663e\u793a6\u81f317 \u5c81\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u4e2d\u67090.3%\u66fe\u88ab\u8bca\u65adTS\uff08Charania \u7b49\uff0c2022\uff09\u3002\u7cfb\u7edf\u56de\u987e\u548c\u835f\u8403\u5206\u6790\u663e\u793a\uff0c\u5168\u7403\u5305\u62ec\u6210\u4eba\u5728\u5185\u7684TS\u60a3\u75c5\u7387\u4e3a0.5-0.6%\uff0c\u513f\u7ae5\u548c\u9752\u5c11\u5e74\u4eba\u7fa4\u4e3a0.7%\uff08Jafari et al\uff0c2022\uff09\u3002\u5728\u4e9a\u6d32\uff0c\u4f7f\u7528\u4e2d\u56fd\u53f0\u6e7e\u4fdd\u9669\u7814\u7a76\u6570\u636e\u5e93\u4f30\u8ba12007-2015\u5e74TS\u548c\u6162\u6027\u62bd\u52a8\u969c\u788d\uff08TS\/CTD\uff09\u7684\u53d1\u751f\u7387\u548c\u60a3\u75c5\u7387\uff08Chou et al. 2022\uff09\u3002\u5728\u6b64\u671f\u95f4\uff0cTS\/CTD \u7684\u60a3\u75c5\u7387\u6709\u6240\u589e\u52a0\u3002TS\/CTD\u7684\u5e74\u53d1\u75c5\u7387\u5728\u513f\u7ae5\u671f\u548c\u9752\u5c11\u5e74\u671f\u589e\u52a0\uff0c\u4f46\u5728\u6210\u5e74\u671f\u4e0b\u964d\u3002\u5728\u4e2d\u56fd\uff0c6-16\u5c81\u5728\u6821\u5b66\u751f\u4e2d\u62bd\u52a8\u969c\u788d\u7684\u60a3\u75c5\u7387\u4e3a1.37%\uff0c\u4f4e\u4e8e\u51e0\u4e4e\u6240\u6709\u5176\u4ed6\u8fd1\u671f\u7814\u7a76\uff08Yan et al. 2022\uff09\u3002TS\u548c\u5f3a\u8feb\u75c7\u9ad8\u5ea6\u5171\u60a3\u3002<\/p><p><br><\/p><p>\u7f8e\u56fd\u75be\u75c5\u63a7\u5236\u4e0e\u9884\u9632\u4e2d\u5fc3 (CDC) \u7684\u4e00\u4efd\u62a5\u544a\u5c1d\u8bd5\u7efc\u5408\u6709\u5173\u7f8e\u56fd\u6301\u7eed\u6027\uff08\u6162\u6027\uff09\u62bd\u52a8\u969c\u788d\u60a3\u75c5\u7387\u7684\u5404\u79cd\u6570\u636e\uff08Tinker et al\uff0c2022 \u5e74\uff09\u3002\u4ed6\u4eec\u4f30\u8ba1\u6709 350,000-400,000 \u540d\u513f\u7ae5\u548c\u6210\u4eba\u60a3\u6709 TS\uff0c\u8fd8\u6709\u5927\u7ea6 100 \u4e07\u4eba\u60a3\u6709\u6301\u7eed\u6027\u8fd0\u52a8\u6216\u53d1\u58f0\u62bd\u52a8\u969c\u788d\uff0c\u4f46\u4ed6\u4eec\u5f97\u51fa\u7684\u7ed3\u8bba\u662f\uff1a\u4e3a\u4e86\u7814\u7a76\u7ed3\u679c\u66f4\u4ee4\u4eba\u4fe1\u670d\uff0c\u9700\u8981\u91c7\u7528\u66f4\u51c6\u786e\u7684\u65b9\u6cd5\u83b7\u5f97\u65b0\u6570\u636e\u3002<\/p><div><br><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5615b2e elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"5615b2e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-bff830e\" data-id=\"bff830e\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-55e2e0c elementor-widget__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"55e2e0c\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u6d41\u884c\u75c5\u5b66\u9884\u540e\u548c\u81ea\u7136\u53f2<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-92fd514 elementor-widget__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"92fd514\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Ricketts \u56e2\u961f\u4f7f\u7528\u591a\u5143\u7ebf\u6027\u56de\u5f52\u5206\u6790\u8bc4\u4f30\u4e86\u6210\u4eba\u62bd\u52a8\u4e25\u91cd\u7a0b\u5ea6\u53ca\u635f\u5bb3\u7684\u513f\u7ae5\u671f\u9884\u6d4b\u56e0\u7d20\uff0c\u53d1\u73b0\u513f\u7ae5\u671f\u62bd\u52a8\u4e25\u91cd\u7a0b\u5ea6\u548c\u5973\u6027 (p &gt; 0.002) \u662f\u6210\u5e74\u62bd\u52a8\u4e25\u91cd\u7a0b\u5ea6\u548c\u635f\u5bb3\u7684\u91cd\u8981\u9884\u6d4b\u56e0\u7d20 (Ricketts et al. 2022d) \u3002<\/p><p>\u901a\u8fc7\u5728\u7ebf\u8c03\u67e5\uff0c351 \u540d\u60a3\u6709TS\u7684\u6210\u5e74\u7537\u6027\u5b8c\u6210\u4e86\u6709\u5173\u4e0d\u826f\u7ae5\u5e74\u7ecf\u5386 (ACE) \u7684\u8c03\u67e5\u95ee\u5377\u548c\u8036\u9c81\u5927\u5b66\u5168\u7403\u62bd\u52a8\u4e25\u91cd\u7a0b\u5ea6\u91cf\u8868\u7684\u7ec8\u8eab\u7248\u672c\uff08Yang et al\uff0c2022\uff09\u3002\u53d1\u73b0ACE\u4e0e\u8f83\u9ad8\u7a0b\u5ea6\u7684\u7ec8\u8eab\u62bd\u52a8\u7684\u4e25\u91cd\u7a0b\u5ea6\u53ca\u635f\u4f24\u4e4b\u95f4\u5b58\u5728\u5173\u8054\uff0c\u6b64\u5916\uff0cTS\u7684\u9057\u4f20\u98ce\u9669\u53ef\u80fd\u4f1a\u8c03\u8282 ACE \u8bc4\u5206\u4e0e\u62bd\u52a8\u969c\u788d\u4e4b\u95f4\u7684\u5173\u8054\u3002<\/p><p>Openneer \u56e2\u961f\u5bf9\u6b27\u6d32\u591a\u4e2d\u5fc3\u513f\u7ae5\u62bd\u52a8\u7814\u7a76 (EMTICS) \u8fdb\u884c\u4e86\u4e9a\u5206\u6790\uff0c\u4ee5\u8bc4\u4f30\u524d\u77bb\u6027\u7814\u7a76\u4e2d\u62bd\u52a8\u7684\u9884\u6d4b\u56e0\u7d20\uff08Openneer et al\uff0c2022\uff09\u3002\u53d1\u751f\u62bd\u52a8\u7684\u513f\u7ae5\u7537\u6027\u8f83\u591a\uff0c\u4e0e\u6ca1\u6709\u62bd\u52a8\u7684\u513f\u7ae5\u76f8\u6bd4\uff0c\u4ed6\u4eec\u53d1\u751f\u884c\u4e3a\u95ee\u9898\u3001\u81ea\u95ed\u75c7\u8c31\u7cfb\u969c\u788d (ASD) \u75c7\u72b6\u3001\u5f3a\u8feb\u884c\u4e3a\u548c\u60c5\u7eea\u95ee\u9898\u7684\u57fa\u7ebf\u4e25\u91cd\u7a0b\u5ea6\u66f4\u9ad8\u3002\u6709\u8da3\u7684\u662f\uff0c\u4e0d\u540c\u6027\u522b\u4e4b\u95f4\u7684\u62bd\u52a8\u9884\u6d4b\u56e0\u7d20\u5b58\u5728\u5dee\u5f02\uff1a\u884c\u4e3a\u548c\u81ea\u95ed\u75c7\u8c31\u7cfb\u969c\u788d\u95ee\u9898\u662f\u7537\u6027\u7279\u6709\u7684\u9884\u6d4b\u56e0\u7d20\uff0c\u800c\u5f3a\u8feb\u884c\u4e3a\u7684\u4e25\u91cd\u7a0b\u5ea6\u4ee5\u53ca\u5bf9\u7acb\u548c\u60c5\u7eea\u95ee\u9898\u662f\u5973\u6027\u7279\u6709\u7684\u9884\u6d4b\u56e0\u7d20\u3002<\/p><p>Katz\u56e2\u961f\u53d1\u8868\u4e86\u5bf9\u62bd\u52a8\u6027\u5f3a\u8feb\u75c7 (Tourettic OCD\uff0cTOCD\u6307\u8868\u73b0\u51fa\u660e\u663e\u7684\u6162\u6027\u62bd\u52a8\u53ca\u5f3a\u8feb\u7684\u75c7\u72b6\u91cd\u53e0\uff09) \u7684\u975e\u5e38\u5b8c\u6574\u7684\u8bc4\u8bba\u548c\u6982\u8ff0 (Katz et al. 2022)\u3002\u8fd9\u79cd\u8868\u578b\u4e3a\u6240\u6709\u6cbb\u7597 TS \u60a3\u8005\u7684\u4e34\u5e8a\u533b\u751f\u6240\u719f\u77e5\uff0c\u5305\u62ec\u89e6\u6478\u884c\u4e3a\u3001\u5bf9\u79f0\u6027\u95ee\u9898\u548c\u7cbe\u786e\u6027\u601d\u7ef4\u3002\u4f5c\u8005\u8ba4\u4e3a\uff0c\u8fd9\u79cd\u73b0\u8c61\u7684\u6838\u5fc3\u662f\u9700\u8981\u91cd\u590d\u590d\u6742\u7684\u62bd\u52a8\uff0c\u76f4\u5230\u201c\u6070\u5230\u597d\u5904\u201d\uff0c\u800c\u4e0d\u5b58\u5728\u8ba4\u77e5\u6216\u60f3\u8c61\u7684\u5f3a\u8feb\u3002\u4f5c\u8005\u63d0\u51fa\u4e86\u4e3a\u4ec0\u4e48 TOCD \u53ef\u80fd\u662f\u4e00\u79cd\u4e0d\u540c\u4e8e TS \u548c OCD \u7684\u75c5\u75c7\uff0c\u5e76\u4e3b\u5f20\u5c06\u5176\u4f5c\u4e3a\u4e00\u4e2a\u5355\u72ec\u7684\u75c5\u79cd\u7eb3\u5165 DSM \u7684\u672a\u6765\u7248\u672c\u4e2d\u3002\u5c3d\u7ba1\u76ee\u524d\u8fd8\u7f3a\u4e4f\u4e00\u4e9b\u5fc5\u8981\u7684\u8bc1\u636e\uff0c\u4f5c\u8005\u5efa\u8bae\u8fdb\u884c\u4e00\u4e9b\u7814\u7a76\uff0c\u6216\u8bb8\u53ef\u4ee5\u8ba9\u6211\u4eec\u5c06 TOCD \u4e0e TS \u548c OCD \u660e\u786e\u533a\u5206\u5f00\u6765\uff08Robins \u548c Guze 1970\uff09\u3002<\/p><p>Li\u56e2\u961f\u62a5\u9053\u4e86\u60a3\u6709\u96be\u6cbb\u6027 TS \u7684\u513f\u7ae5\uff08Li et al. 2022\uff09\u3002\u513f\u7ae5\u96be\u6cbb\u6027 TS \u7684\u7279\u70b9\u662f\u53d1\u75c5\u5e74\u9f84\u8f83\u65e9\u3001\u75c5\u7a0b\u8f83\u957f\u3001\u667a\u5546\u8f83\u4f4e\u3001\u9884\u611f\u51b2\u52a8 (PU) \u53d1\u751f\u7387\u8f83\u9ad8\u4ee5\u53ca\u7cbe\u795e\u5408\u5e76\u75c7\u53d1\u751f\u7387\u8f83\u9ad8\u3002<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-82edaff elementor-widget elementor-widget-text-editor\" data-id=\"82edaff\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u611f\u89c9\u73b0\u8c61\u548c\u9884\u5146\u51b2\u52a8<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-231e151 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"231e151\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-09ae196\" data-id=\"09ae196\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-eeb8209 elementor-widget__width-inherit elementor-widget elementor-widget-text-editor\" data-id=\"eeb8209\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>\u4eca\u5929\u7684\u5206\u4eab\u5c31\u5230\u8fd9\u91cc\u4e86\uff0c\u4ece\u4eca\u5929\u7684\u5206\u4eab\u4e2d\u53ef\u4ee5\u770b\u51fa\uff0c\u513f\u7ae5\u671f\u62bd\u52a8\u7684\u9884\u6d4b\u56e0\u7d20\u662f\u76ee\u524d\u79d1\u7814\u5173\u6ce8\u8f83\u591a\u7684\u70ed\u70b9\uff0c\u5982\uff1a\u513f\u7ae5\u671f\u62bd\u52a8\u4e25\u91cd\u7a0b\u5ea6\u548c\u5973\u6027 (p &gt; 0.002) 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